AHIP praised the Supreme Court's decision to uphold the constitutionality of the inter partes patent review process, noting its importance for preventing inappropriate tactics to prolong patent monopolies on brand-name drugs. "By upholding a faster and less costly patent review process, the Supreme Court has protected an important pathway that allows generic prescription drugs to get to patients faster. Generic drugs increase competition and choice in the market, which helps to lower drug prices," the group said.
A combination of 400 milligrams of ibuprofen and 1,000 milligrams of acetaminophen relieves dental pain better than prescription opioids and causes fewer side effects, according to a review of more than 460 published studies. The findings, published in The Journal of the American Dental Association, suggest that use of common nonsteroidal anti-inflammatory drugs, with or without acetaminophen, "offers the most favorable balance between benefits and harms, optimizing efficacy while minimizing acute adverse events," study co-author Anita Aminoshariae said.
The FDA said it is re-evaluating the safety of Nuplazid, the only medication approved to treat hallucinations and delusions tied to Parkinson's disease psychosis, after it was linked to hundreds of deaths. An analysis by the Institute for Safe Medication Practices showed that during the first 10 months Nuplazid was available, 244 deaths were reported involving Nuplazid as a "suspect" medication, and reported deaths now number more than 700, according to the FDA.
Veterinarians face the difficult task of reducing and replacing antimicrobials while maintaining livestock animal health or commercial productivity, says veterinarian Mark White, president of the British Veterinary Association's Pig Veterinary Society. Experts in the US say appropriate use data are lacking and misinformation is abundant, but the FDA has funded efforts to collect data that could be used to develop evidence-based drug stewardship guidance for livestock.
Researchers at the Cornell University College of Veterinary Medicine believe bovine mammary stem cell secretions can heal tissue damaged by mastitis. The researchers identified secretions involved in blood vessel formation, cellular migration and protection against toxins from Gram-negative and other bacteria.
The American College of Obstetricians and Gynecologists this week recommended women receive treatment for a "fourth trimester," beginning within three weeks of birth and focusing on maternal physical, social and psychological well-being. The recommendation for ongoing care, published in Obstetrics & Gynecology, called for an initial postpartum assessment and follow-up to include issues such as emotional well-being, infant care, sexuality, contraception and sleep.
Researchers conducted a systematic review of 26 research articles and found that issues pertaining to interoperability, cost and productivity are main reasons that providers change EHR vendors. The findings, published in Perspectives in Health Information Management, also showed that data exchange was an important functionality that providers look for in a replacement EHR system.
Patients with type 2 diabetes had lower aortic distensibility, an indication of aortic stiffness, and increased concentric left ventricular remodeling and LV mass, compared with those without diabetes, according to a study in Diabetes. UK researchers suggested focusing treatment on aortic stiffness to help patients with diabetes prevent the development of heart failure.
A study in Acta Diabetologica showed a significant association between increased sedentary time and higher depression symptoms and lower diabetes self-efficacy among women with type 2 diabetes, but not among male patients. Researchers conducted a cross-sectional study involving 163 diabetes patients, mean age of 62.7, and found that increased physical activity was associated with higher diabetes self-efficacy in male patients and higher social support rates in female patients.
UK researchers evaluated 54,803 adults with type 1 or type 2 diabetes, age at least 70, and found a substantial increase in mortality risk as A1C variability increased in gender-based analyses and in all models for the overall cohort. The findings were published in The Lancet Diabetes & Endocrinology.
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