Yale University researchers who used PET with the new radiotracer C-11-UCB-J found that individuals with mild Alzheimer's disease dementia had 41% lower hippocampal synaptic vesicle glycoprotein 2A markers, compared with healthy controls. The approach, described in JAMA Neurology, may be used not only in diagnosing, monitoring and treating Alzheimer's disease, but also in other disorders such as Parkinson's disease, epilepsy and schizophrenia, researcher Dr. Ming-Kai Chen said.
The FDA has given Stryker premarket approval for its Surpass Streamline flow diverter, a cobalt chromium braided stent, for use in the treatment of unruptured large and giant wide-neck intracranial aneurysms. The device facilitates aneurysm occlusion and maintains perforator artery patency as it opens and delivers consistent mesh density across the aneurysm neck.
A study in a radiology journal showed that secondary imaging interpretations across various imaging modalities broadly increased between 2003 and 2016, with billed secondary imaging interpretations totaling more than 9.7 million for radiography and fluoroscopy and 23,120 for nuclear medicine in 2016. The findings also showed that denial rates in 2016 remained lower than 25% across all imaging service families.
House Ways and Means Committee Chairman Kevin Brady, R-Texas, said he is talking with HHS Secretary Alex Azar about how to resume Affordable Care Act risk adjustment payments after the administration suspended them earlier this month. House lawmakers intend to consider a number of health care bills next week, including legislation to expand health savings accounts and postpone or repeal certain Affordable Care Act taxes, but Brady said he's not sure if a risk adjustment fix will be among the measures.
Five Democratic lawmakers sent a letter to HHS Secretary Alex Azar and CMS Administrator Seema Verma urging them to reverse their decision to suspend Affordable Care Act risk adjustment payments to insurers. The suspension will "further destabilize the individual and small group markets that millions of Americans rely on for health insurance" and it could force insurers to leave the individual markets or raise premiums, they wrote.
In the journal PLOS ONE, researchers described how nursing notes could be used as part of models to predict 30-day mortality among patients in intensive care units. The team applied a sentiment analysis algorithm to notes for more than 27,000 patients, finding the notes improved mortality predictions, and the authors say analysis of notes might also improve predictions for recovery from infection or readmission.
A diet that includes consumption of full-fat milk and cheese may reduce the risk of cardiovascular disease, a new study has found. Researchers followed 3,000 seniors and at intervals measured levels of three fatty acids found in dairy products, finding those who had higher levels of one of the fatty acids were 42% less likely to die of stroke.
Women with type 1 diabetes and elevated glycated hemoglobin levels at or near the time of conception are more likely to give birth to infants with major cardiac defects compared with women who do not have diabetes, a study in The BMJ showed. Researchers said the study supports earlier findings of an increased risk of birth defects in infants whose mothers have type 1 diabetes.
The number of Sun Life Financial clients whose annual medical care costs reached at least $1 million soared by almost 90% from 2014 to 2017, according to a company report. Among the drivers was the use of high-cost injectable drugs, which accounted for 6.6% of aggregate claims for patients whose costs totaled or exceeded $1 million.