The MS Society Tissue Bank is in its 20th year of brain and spinal cord tissue collection, which is used in multiple sclerosis research projects all over the world. More than 700 people have donated in the bank, but there is continued demand from MS researchers.
Massachusetts Eye and Ear Infirmary surgeon Emma Davies says cornea transplants are the best treatment for Fuchs dystrophy. "There's not a day that goes by that I don't think of, with gratitude, of that family or the patient who made that decision so that now I can see," transplant recipient Mary Lou Hackett said.
The Susan G. Komen Tissue Bank will hold a healthy breast tissue collection event in March at Banner MD Anderson Cancer Center in Gilbert, Ariz. "By donating normal breast tissue, a woman can help scientists understand more about breast cancer. We believe that this is a truly genuine and personal way for women to contribute to breast cancer research," Dr. Lida Mina said.
NIH researchers ended a clinical trial after healthy volunteers taking a combination of the HIV drug dolutegravir and the tuberculosis treatment isoniazid-rifapentine had "unexpected and serious toxicities," according to a report in the journal Clinical Infectious Diseases. Two of four participants developed influenza-like syndrome and one was hospitalized for a day, and researchers said the drugs should be combined "cautiously, ideally in a clinical research setting."
The American College of Surgeons is calling for teachers to receive "Stop the Bleed" training and for school systems to put stop-bleeding kits in every classroom. Training in basic bleeding-control techniques can save lives, said Dr. Jeff Kerby of the University of Alabama at Birmingham School of Medicine.
The Global Commission to End the Diagnostic Odyssey for Children, formed by Shire, Microsoft and EURODIS Rare Diseases Europe, will form a multidisciplinary group of experts with the goal of expediting the diagnosis of children with rare diseases. "We're seeking innovative ways to integrate emerging technologies into our efforts, which will play a critical role as we strive to impact the diagnosis journey," said Microsoft Chief Medical Officer and Senior Director Dr. Simon Kos.
Celularity, a stem cell startup that collects placenta stem cells for health care products, has raised $250 million. The company is selling wound-healing products and developing immunotherapies.
Three studies in the journal Science detailed how CRISPR gene-editing technology can be used to advance disease detection and treatment. DNA Endonuclease Targeted CRISPR Trans Reporter, or DETECTR, is being developed to identify human papillomavirus strains; SHERLOCK version 2.0 can detect and distinguish Zika or dengue viruses in blood samples; and the CRISPR-mediated analog multi-event recording apparatus, or CAMERA, is being developed to make cells record exposure to pollutants.
A study in the journal Cell Reports described how scientists found the Pi4Ka gene played an important role in blood cell development but can also lead to forms of hematologic malignancy and anemia when disrupted.
In Angola and the Democratic Republic of the Congo, fractional doses of yellow fever vaccine stretched the supply and allowed more people to be vaccinated. Researchers reported in The New England Journal of Medicine that the smaller doses resulted in high rates of immune response.
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