The number of confirmed cases of dengue in India has reached 8,063, with 4,188 of those located in Delhi. Indian health officials also reported that the number of recorded cases of malaria as of Saturday stands at 1,106, while the number of chikungunya cases has reached 855.
Aidan Hooper of Edmond, Okla., died in an accident when he was 8 years old. Aidan, whose donated heart valves gave lives to two young girls, will be honored as a tissue donor in the 2018 Tournament of Roses Parade.
A study evaluating wait-listing for 1,057 patients who were referred for kidney transplant evaluation found African-American patients were less likely than white patients to be wait-listed for transplant, and wait-listing was positively associated with income, transplant knowledge and having a live donor. Wait-listing was negatively associated with factors including age, comorbidities, being on dialysis and low socioeconomic status, researchers reported at the American Society of Nephrology annual meeting.
A review in the journal Hepatology found that patients coinfected with hepatitis C virus and HIV experienced sustained virologic response (SVR) at similar rates after treatment with direct-acting antiviral therapies as patients infected with HCV alone. In contrast, coinfected patients assigned to interferon-based treatment were less likely to achieve SVR than monoinfected patients.
Seasonal malaria chemoprevention, an older process that involves providing patients with a monthly combination dose of antimalarial drugs during the rainy season, was found to reduce the prevalence of malaria in West African children by up to 84%, according to data reported at a meeting of the American Society of Tropical Medicine and Hygiene. Seasonal malaria chemoprevention involves combining three drugs, sulphadoxine, pyrimethamine and amodiaquine, which will not negate the efficacy of the malaria drug artemisinin once that is taken.
Medivir reports it has launched a cancer initiative called Leukotide that will produce a new acute myeloid leukemia drug that can also treat other blood disorders. The new drug is intended to be more effective and better tolerated to improve outcomes for AML and other hematological cancer patients.
A distribution deal has been completed between Sysmex Asia Pacific and Genedrive for marketing rights to the latter's HCV ID kit and PCR platform for the Asia Pacific region. The partners plan to pursue regulatory approvals in a number of Asian countries for the assay.
The California Institute for Regenerative Medicine, a $3 billion stem cell research program, is expected to outline a strategy for continuing operations after 2020 at a meeting scheduled for Nov. 27. The resulting plans will go before the agency's full board for ratification in December. Funding options reportedly under consideration as of September included a potential merger with a private entity or a bond measure to raise money.
Homology Medicines will allow Novartis to use its proprietary adeno-associated virus gene-editing platform technology in the development of new treatments for certain eye diseases and a blood disorder. Financial details of the agreement were undisclosed.
The US is one of 22 countries engaged in the elimination of the hepatitis C virus, but only nine nations are making progressive headway toward total elimination by 2030, according to the Polaris Observatory, which provides data on hepatitis B and C elimination. Australia, Egypt, France, Georgia, Germany, Iceland, Japan, the Netherlands and Qatar are slated to eliminate HCV by 2030, the target date set by the World Health Organization.